Tenecteplase for Thrombectomy Thrombolysis

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Thrombolysis for acute ischemic stroke by tenecteplase in the emergency department of a Moroccan hospital

INTRODUCTION Thrombolysis has radically changed the prognosis of acute ischemic stroke. Tenecteplase is a modified form of rt-PA with greater specificity for fibrin and a longer half-life. We report the experience of a Moroccan tertiary hospital in thrombolysis using Tenecteplase. METHODS We conducted an open prospective study of all patients who were treated with Tenecteplase for an acute is...

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Intravenous thrombolysis and thrombectomy in young patients with ischaemic stroke

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Orolingual and abdominal angioedema post thrombolysis and thrombectomy.

A 53-year-old man treated with an angiotensin-converting enzyme (ACE) inhibitor presented with left hemiplegia (NIH Stroke Scale 23). Magnetic resonance angiography revealed a right proximal middle cerebral artery occlusion (figure 1). Thirty minutes after thrombolysis, orolingual swelling was observed. Two hours later, just after mechanical thrombectomy was completed, he developed painful abdo...

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Thrombolysis versus thrombectomy in acute deep vein thrombosis

Deep vein thrombosis (DVT) is a significant health problem leading to the admission of over 250,000 Americans each year. Its most serious acute complication, namely pulmonary embolus kills approximately 100,000 each year, and is the third most common cardiovascular related mortality after myocardial infarction and stroke. Chronic leg problems following DVT include leg heaviness, tiredness, cram...

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Tenecteplase versus alteplase before endovascular thrombectomy (EXTEND-IA TNK): A multicenter, randomized, controlled study.

Background and hypothesis Intravenous thrombolysis with alteplase remains standard care prior to thrombectomy for eligible patients within 4.5 h of ischemic stroke onset. However, alteplase only succeeds in reperfusing large vessel arterial occlusion prior to thrombectomy in a minority of patients. We hypothesized that tenecteplase is non-inferior to alteplase in achieving reperfusion at initia...

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ژورنال

عنوان ژورنال: Neurosurgery

سال: 2018

ISSN: 0148-396X,1524-4040

DOI: 10.1093/neuros/nyy506